Simon R Johnson Selected Research

trans-sodium crocetinate (crocetin)

11/2021	Lymphangioleiomyomatosis: pathogenesis, clinical features, diagnosis, and management.
1/2021	Machine learning can predict disease manifestations and outcomes in lymphangioleiomyomatosis.
1/2021	Mast-Cell Tryptase Release Contributes to Disease Progression in Lymphangioleiomyomatosis.
1/2020	Sphingolipid, fatty acid and phospholipid metabolites are associated with disease severity and mTOR inhibition in lymphangioleiomyomatosis.
1/2019	Tuberous Sclerosis Complex (TSC): Expert Recommendations for Provision of Coordinated Care.
11/2016	The economic burden of tuberous sclerosis complex in the UK: A retrospective cohort study in the Clinical Practice Research Datalink.
3/2016	The clinical profile of tuberous sclerosis complex (TSC) in the United Kingdom: A retrospective cohort study in the Clinical Practice Research Datalink (CPRD).
10/2014	Natural history of angiomyolipoma in lymphangioleiomyomatosis: implications for screening and surveillance.
8/2010	Role of the CXCR4/CXCL12 axis in lymphangioleiomyomatosis and angiomyolipoma.
3/2009	Analysis of the oestrogen response in an angiomyolipoma derived xenograft model.

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Simon R Johnson Research Topics

Disease

34	Lymphangioleiomyomatosis (Lymphangiomyomatosis) 04/2022 - 04/2002
16	Tuberous Sclerosis (Bourneville's Disease) 01/2022 - 04/2002
9	Lung Diseases (Lung Disease) 01/2022 - 02/2007
9	Cysts 01/2021 - 04/2002
9	Angiomyolipoma 01/2021 - 04/2002
8	Rare Diseases (Rare Disease) 12/2018 - 04/2002
8	Chronic Obstructive Pulmonary Disease (COPD) 12/2018 - 06/2008
7	Asthma (Bronchial Asthma) 01/2022 - 08/2004
7	Pneumothorax 01/2021 - 04/2002
6	Respiratory Insufficiency (Respiratory Failure) 11/2021 - 07/2010
5	Neoplasms (Cancer) 11/2021 - 04/2002
3	Disease Progression 01/2021 - 06/2015
2	Idiopathic Pulmonary Fibrosis 01/2022 - 01/2018
2	Airway Remodeling 01/2022 - 08/2004
2	Lymphatic Abnormalities 01/2020 - 10/2014
2	Nausea 01/2018 - 02/2007
2	Inborn Genetic Diseases (Disease, Hereditary) 11/2016 - 03/2016
2	Fatigue 05/2009 - 02/2007
1	COVID-19 01/2022
1	Eosinophilia 01/2021
1	Carcinogenesis 01/2021
1	Airway Obstruction (Choking) 10/2019
1	Rupture 12/2018
1	Menstruation Disturbances 01/2018
1	Acne Vulgaris 01/2018
1	Ulcer 01/2018
1	Breast Neoplasms (Breast Cancer) 02/2016
1	Lung Injury 01/2016
1	Fibrosis (Cirrhosis) 01/2016
1	Pulmonary Fibrosis (Fibrosing Alveolitis) 01/2016
1	Inflammation (Inflammations) 01/2015
1	Hemorrhage 10/2014
1	Lymphatic Diseases 04/2012
1	Interstitial Lung Diseases (Interstitial Lung Disease) 03/2012
1	Emphysema 11/2011
1	Spontaneous Abortion (Miscarriage) 05/2009
1	Premature Birth (Birth, Premature) 05/2009

Drug/Important Bio-Agent (IBA)

30	lipoarabinomannan (LAM)IBA 04/2022 - 04/2002
12	trans-sodium crocetinate (crocetin)IBA 11/2021 - 04/2002
9	Proteins (Proteins, Gene)FDA Link 01/2020 - 04/2002
8	Sirolimus (Rapamycin)FDA Link 01/2022 - 01/2008
8	Matrix Metalloproteinases (MMPs)IBA 01/2019 - 08/2004
5	Peptide Hydrolases (Proteases)FDA Link 12/2018 - 01/2010
4	Biomarkers (Surrogate Marker)IBA 01/2021 - 04/2012
3	CollagenIBA 01/2022 - 01/2014
3	Doxycycline (Periostat)FDA LinkGeneric 05/2014 - 09/2010
2	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2022 - 01/2016
2	EnzymesIBA 01/2019 - 06/2008
2	Protease Inhibitors (Protease Inhibitor)IBA 12/2018 - 01/2010
2	Pancreatic Elastase (Elastase)IBA 12/2018 - 06/2008
2	Matrix Metalloproteinase 1 (Interstitial Collagenase)IBA 01/2017 - 01/2014
2	TOR Serine-Threonine KinasesIBA 08/2010 - 01/2007
1	MTOR InhibitorsIBA 04/2022
1	Protein-Lysine 6-Oxidase (Lysyl Oxidase)IBA 01/2022
1	OvalbuminIBA 01/2022
1	rasagiline (Azilect)FDA Link 01/2021
1	Interleukin-33IBA 01/2021
1	Clorgyline (Clorgiline)IBA 01/2021
1	Histamine (Histamine Dihydrochloride)FDA Link 01/2021
1	Histidine (L-Histidine)FDA Link 01/2021
1	Oxidoreductases (Dehydrogenase)IBA 01/2021
1	Histamine H1 Receptors (Histamine H1 Receptor)IBA 01/2021
1	Loratadine (Alavert)FDA Link 01/2021
1	Tryptases (Tryptase)IBA 01/2021
1	Fatty Acids (Saturated Fatty Acids)IBA 01/2020
1	Phospholipids (Phosphatides)FDA LinkGeneric 01/2020
1	SphingolipidsIBA 01/2020
1	Messenger RNA (mRNA)IBA 01/2020
1	Protein Isoforms (Isoforms)IBA 01/2020
1	SteroidsIBA 10/2019
1	Bronchodilator Agents (Bronchodilators)IBA 10/2019
1	Adrenal Cortex Hormones (Corticosteroids)IBA 10/2019
1	DefensinsIBA 12/2018
1	AminesIBA 12/2018
1	Complement System Proteins (Complement)IBA 12/2018
1	MucinsIBA 12/2018
1	Vitamin D-Binding ProteinIBA 11/2018
1	Cathepsin KIBA 08/2017
1	Methacholine Chloride (Methacholine)FDA Link 01/2017
1	Metalloproteases (Metalloproteinases)IBA 02/2016
1	GelatinIBA 01/2016
1	Hydroxyproline (4 Hydroxyproline)IBA 01/2016
1	Bleomycin (Blenoxane)FDA LinkGeneric 01/2016
1	Secretory Leukocyte Peptidase InhibitorIBA 01/2016
1	Simvastatin (Zocor)FDA LinkGeneric 01/2015
1	TenascinIBA 01/2014
1	Vascular Endothelial Growth Factor DIBA 04/2012
1	Certolizumab Pegol FDA Link 03/2012
1	Mechanistic Target of Rapamycin Complex 1IBA 06/2011
1	plerixafor FDA Link 08/2010
1	platelet-derived growth factor C (PDGF-C)IBA 03/2009
1	GelatinasesIBA 06/2008
1	ImmunosorbentsIBA 06/2008
1	Collagenases (Collagenase)FDA Link 06/2008
1	Biotin (Vitamin H)FDA Link 06/2008

Therapy/Procedure

11	Therapeutics 01/2022 - 01/2008
3	Lung Transplantation 04/2022 - 07/2010
1	Pleurodesis 11/2017
1	Nephrectomy 10/2014
1	Transplantation 07/2010